A combined procedure to deliver autologous mesenchymal stem cells to the patients with traumatic brain injury

Z-X Zhang, L-X Guan, K Zhang, Q Zhang, L-J Dai: A combined procedure to deliver  autologous mesenchymal stromal cells to patients with traumatic brain injury.  Cytotherapy 10:134-139, 2008.

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There is increasing evidence of therapeutic benefits from bone marrow
(BM)-derived mesenchymal stromal cells (MSC) in various animal
models with neurologic disorders. It is of great interest to apply the
approach to clinical patients, i.e. to take the investigations from
laboratory bench to the patient’s bedside. This clinical trial was
performed to assess the safety and feasibility of a combined procedure to
deliver autologous MSC to patients with traumatic brain injury.

Abstract There is increasing evidence of therapeutic benefits from bone marrow (BM)-derived mesenchymal stromal cells (MSC) in various animal models with neurologic disorders. It is of great interest to apply the approach to clinical patients, i.e. to take the investigations from laboratory bench to the patient’s bedside. This clinical trial was performed to assess the safety and feasibility of a combined procedure to deliver autologous MSC to patients with traumatic brain injury.

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