Autotransplantation of purified mesenchymal stem cells in a patient with acute myocardial infarction: A case study
Thursday, September 17th, 2009Zhen-Xing Zhang, Yan-Zhen Zhang, Li-Xue Guan, Yan-Ju Zhou, Xin-Xiang Zhao, Yao-Hong Cai, Li-Mei Zhao, Feng-Qi Li, Long-Jun Dai: Autotransplantation of purified mesenchymal stem cells in a patient with acute myocardial infarction: A case study. Journal of Stem Cells 2(3):185-189, 2007.
Abstract Purified bone marrow-derived mesenchymal stem cells were autotransplanted to a patient with acute myocardial infarction. The employment of the sub-population of bone marrow-derived mononuclear cells was nitended to clarify some disputable outcomes in hetrogeneous mononuclear cell therapy. The improvement of myocardial perfusion and cardiac function was observed after delivery of mesenchymal stem cells through a combined procedure of primary intracoronary infusion and secondary intraveneous infusion. This procedure is expected to enhance the engraftment efficacy of transplanted cells at infarcted myocardium.
Download paper